New Selenium-based Targeted Nanocapsules to treat Breast Cancer.
Nanomedicine is an emerging interdisciplinary field encompassing nanotechnology, biology, and medicine, which employ converging technologies to improve human health. The NEOSETAC project is focused on the nanomedicine field and its major goal is to develop a new selenium-based targeted nanocapsules to treat breast cancer. Selenium-containing nanoparticles have excellent biological activities and low toxicity and have recently emerged as potential cancer therapeutic payloads. The overall research and development goal of the proposed action is twofold: to design and manufacture the selenium-capsules to treat breast cancer and demonstrate their therapeutic potential in pre-clinical studies. The research and development activities under the NEOSETAC project focus on in-depth investigation and tests of a new drug for breast cancer, so the results will be of great value to the industry but also will improve the skills and knowledge in the matter of the involved researchers.
In the NEOSETAC project, breast cancer will be the focus of study being the most common cancers in women. It comprises of 10.4% of all the cancer incidences among women, causing 411.093 deaths per year all over the world.
The NEOSETAC project is part of the Industry-Academia Partnerships and Pathways project (IAPP) and allows to develop permanent international and inter-sector collaborations between academic research centers and industrial organizations.
Academic Industry R&D Opportunities for Picornaviruses. AIROPico
This Research Project will generate more knowledge on commonly encountered infections of human picornaviruses like the common cold or meningitis. This knowledge will give us more insight in these virus infections and the disease they cause. Based on these insights effective antiviral treatments will be developed.
The project objectives are: WP1) to investigate biological features of clinically relevant picornavirus types to understand basic mechanism of host pathogen interactions; WP2) to develop faster diagnostic detection methods both for routine detection of picornaviruses and for easy-to-use typing tools; and WP3) to generate knowledge and tools necessary to fight picornavirus infections by antibodies and small antiviral.
AIROPico is an Industry-Academia Partnerships and Pathways project (IAPP). It will provide interdisciplinary education and training to company researchers and university scientists. Twenty-one staff exchanges will enforce the collaboration within the Consortium on picornavirus biology, diagnostics and therapy development.
Desarrollo de un test rápido de detección de Piscirickettsia salmonis a partir de anticuerpos monoclonales. SALmAB
Piscirickettsia salmonis is the etiologic agent of Piscirickettsiosis (SRS), a severe systemic fish disease affecting specially salmonids. Piscirickettsiosis has become a serious threat for the worldwide aquaculture industry causing important economic losses, especially in Chile.
To solve the recurring SRS events, the salmon industry has responded by increasing the use of antibiotic-based therapeutic practices. However, the antibiotics may inhibit the growth of the pathogen but are unsuccessful in stopping disease outbreaks.
Therefore, it is important and necessary to prevent and control SRS by developing new diagnostic techniques. In this project, we propose to generate specific monoclonal antibodies and to develop a new lateral flow assay test that allows early detection of P. salmonis in situ and in a time-efficient manner.
The resulting diagnostic tool will have a global impact in the aquaculture world, specifically in the salmon farming field in Chile, Norway, Scotland and Canada.